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CREBBP-IN-1

CREBBP-IN-1 (Compound 10) exhibits good affinity with CREBBP bromodomain with Kd of 0.77 μM[1].

Product Specifications

CAS Number

1801324-41-3

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/crebbp-in-1.html

Smiles

O=C(C1=CC=CC(C(NC2=CC(C(C)=O)=CC=C2OCC)=O)=C1)O

Molecular Formula

C18H17NO5

Molecular Weight

327.33

References & Citations

[1]Xu M, et al., Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics. J Med Chem. 2016 Feb 25;59 (4) :1340-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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