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Purified Anti-Human CD20 Antibody[Rituximab]

Product Specifications

Background

CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.

Abbreviation

CD20/MS4A1

Gene ID

931

UniProt

P11836

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD20 protein

Target

LEU; CVID; B-lymphocyte antigen CD; Leukocyte surface antigen Leu; B-lymphocyte surface antigen B; Membrane-spanning 4-domains subfamily A member; MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; Bp35; Ly-44; APY; ATOPY; B lymphocyte antigen CD20; B Lymphocyte Cell Surface Antigen B1; B-lymphocyte cell-surface antigen B1; Bp 35; CD 20; CD20 antigen; CD20 receptor; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU 16; LEU16; leukocyte surface antigen Leu 16; Ly44; Membrane spanning 4 domains A1; Membrane spanning 4 domains subfamily A member 2; MGC3969

Clonality

Monoclonal

Clone

Rituximab

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Stem Cells; Cancer

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Human IgG1, κ

Available Sizes

Curated Selection

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