Prim-O-glucosylcimifugin
Product Specifications
UNSPSC Description
Prim-O-glucosylcimifugin exerts anti-inflammatory effects through the inhibition of iNOS and COX-2 expression by through regulating JAK2/STAT3 signaling.
Target Antigen
COX; NO Synthase; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Prim-O-glucosylcimifugin.html
Purity
99.94
Solubility
DMSO : ≥ 150 mg/mL
Smiles
COC1=C(C[C@@H](C(C)(O)C)O2)C2=CC(OC(CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)=C1C4=O
Molecular Weight
468.45
References & Citations
[2]Chen N, et al. Prime-O-glucosylcimifugin attenuates lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol. 2013 Jun;16(2):139-47.|[1]Zhou J, et al. Prim-O-glucosylcimifugin Attenuates Lipopolysaccharideinduced Inflammatory Response in RAW 264.7 Macrophages. Pharmacogn Mag. 2017 Jul-Sep;13(51):378-384.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0635/Prim-O-glucosylcimifugin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0635/Prim-O-glucosylcimifugin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
80681-45-4
Available Sizes
Curated Selection
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