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Bofumustine

Bofumustine (ICIG 1105) is a nitrosourea compound with antitumor activity. Bofumustine can interfere with the replication and division of tumor cell DNA through alkylation, leading to the death of tumor cells. Bofumustine can be used in the field of cancer research[1].

Product Specifications

CAS Number

[55102-44-8]

Product Name Alternative

ICIG 1105; NSC 279194; RFCNU

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bofumustine.html

Smiles

ClCCN(N=O)C(NC1[C@@]2([H])[C@@](OC(C)(C)O2)([H])[C@@H](COC(C3=CC=C([N+]([O-])=O)C=C3)=O)O1)=O

Molecular Formula

C18H21ClN4O9

Molecular Weight

472.83

References & Citations

[1]Jun Sun, et al. Anticarcinogen composition carried with both nitrosourea type medicine and guanine analog. CN101045059A. 2007-04-28

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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