2'-Deoxyadenosine-5'-triphosphate

2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase[1].

Product Specifications

CAS Number

[1927-31-7]

Product Name Alternative

DATP

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

DNA/RNA Synthesis; Endogenous Metabolite

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-deoxyadenosine-5-triphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@H](O1)CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C[C@@H]1N2C3=NC=NC(N)=C3N=C2

Molecular Formula

C10H16N5O12P3

Molecular Weight

491.18

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]P J Romaniuk, A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. J Biol Chem. 1982 Jul 10;257 (13) :7684-8.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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