Alpha-1,3-Galactosyltransferase (GTB)

Alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) catalyzes the synthesis of the xenoantigen or α-galactose (α-Gal) epitope. alpha-1,3-Galactosyltransferase (GTB) transfers galactose from UDP-Gal to type 1 or type 2, αFuc1→2βGal-R (H) -terminating acceptors[1].

Product Specifications

CAS Number

[37257-33-3]

Product Name Alternative

Alpha 1,3GT

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/alpha-1-3-galactosyltransferase-gtb.html

Solubility

10 mM in DMSO

Smiles

[alpha-1,3-Galactosyltransferase(GTB)]

References & Citations

[1]Sandra L Marcus, et al. A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase. J Biol Chem. 2003 Apr 4;278 (14) :12403-5.|[2]Nethaji Thiyagarajan, et al. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Sci Rep. 2012;2:940.