Pyridoxal

Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744) . Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS) [1][2][3].

Product Specifications

CAS Number

[66-72-8]

Product Name Alternative

Pyridoxaldehyde

UNSPSC

12352005

Hazard Statement

H302

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pyridoxal.html

Purity

99.95

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=CC1=C(O)C(C)=NC=C1CO

Molecular Formula

C8H9NO3

Molecular Weight

167.16

Precautions

H302

References & Citations

[1]Vrolijk MF, et al. The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Toxicol In Vitro. 2017 Oct;44:206-212. |[2]Aufiero E, et al. Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review. Nutr Rev. 2004 Mar;62 (3) :96-104.|[3]Nagata, Yoshiko, Reiko Yoda, and Yoshikazu Matsushima. "Solvolysis of pyridoxal hydrochloride in alcohols." Chemical and pharmaceutical bulletin 41.6 (1993) : 1019-1022.|[4]Vrolijk, Misha F., et al. "The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function." Toxicology In Vitro 44 (2017) : 206-212.