(±) -Clopidogrel (bisulfate)

(±) -Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±) -Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±) -Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±) -Clopidogrel bisulfate has anti-inflammatory effects[1][2].

Product Specifications

CAS Number

[135046-48-9]

UNSPSC

12352005

Hazard Statement

H314, H411

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/racemic-clopidogrel-bisulfate.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C(C1=C(C=CC=C1)Cl)N2CC3=C(SC=C3)CC2)=O.O=S(O)(O)=O

Molecular Formula

C16H18ClNO6S2

Molecular Weight

419.90

Precautions

H314, H411

References & Citations

[1]Liu O, et al. Clopidogrel, a platelet P2Y12 receptor inhibitor, reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. PLoS One. 2012;7 (12) :e51707.|[2]Hagiwara S, et al. Adenosine diphosphate receptor antagonist clopidogrel sulfate attenuates LPS-induced systemic inflammation in a rat model. Shock. 2011 Mar;35 (3) :289-92.