Ertapenem sodium

Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].

Product Specifications

CAS Number

[153773-82-1]

Product Name Alternative

L-749345; MK-826

UNSPSC

12352005

Hazard Statement

H302, H317

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Ertapenem_sodium.html

Purity

98.94

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C([C@H]1NC[C@@H](SC2=C(C(O)=O)N3[C@]([C@]([C@@H](C)O)([H])C3=O)([H])[C@H]2C)C1)NC4=CC=CC(C(O[Na])=O)=C4

Molecular Formula

C22H24N3NaO7S

Molecular Weight

497.50

Precautions

H302, H317

References & Citations

[1]Kenneth E Aldridge. Ertapenem (MK-0826), a new carbapenem: comparative in vitro activity against clinically significant anaerobes. Diagn Microbiol Infect Dis. 2002 Oct;44 (2) :181-6. |[2]C J Gill, et al. In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, MK-826 (L-749,345) . Antimicrob Agents Chemother. 1998 Aug;42 (8) :1996-2001.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C, sealed storage, away from moisture and light

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Adv Ther (Weinh) . 2024 Jan 12.|Biomed Res Int. 2018 Jul 2:2018:3579832.|J Antimicrob Chemother. 2020 Jul 1;75 (7) :1850-1858.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|J Clin Microbiol. 2024 May 7:e0152023.|Molecules. 2025 Mar 9;30 (6) :1224.|Nat Commun. 2021 Jul 22;12 (1) :4461.|Nat Commun. 2022 Mar 2;13 (1) :1116.|J Antimicrob Chemother. 2023 Sep 5;78 (9) :2242-2253.|Proc Natl Acad Sci U S A. 2024 Jan 16;121 (3) :e2314514121.|Proc Natl Acad Sci U S A. 2025 Dec 2;122 (48) :e2524436122.