ADL-5747
ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR) . By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms[1].
Product Specifications
CAS Number
850176-30-6
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/adl-5747.html
Purity
99.82
Solubility
DMSO : 3.33 mg/mL (ultrasonic)
Smiles
O=C(N(CC)CC)C1=CC=C(C2=CC3(CCNCC3)OC4=C2C=CC=C4)C(O)=C1
Molecular Formula
C24H28N2O3
Molecular Weight
392.49
References & Citations
[1]Le Bourdonnec B, et al. Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N, N-diethyl-3-hydroxy-4- (spiro [chromene-2, 4′-piperidine]-4-yl) benzamide (ADL5747) [J]. Journal of medicinal chemistry, 2009, 52 (18) : 5685-5702.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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