ADL-5747

ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR) . By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms[1].

Product Specifications

CAS Number

[850176-30-6]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/adl-5747.html

Purity

99.82

Solubility

DMSO : 3.33 mg/mL (ultrasonic)

Smiles

O=C(N(CC)CC)C1=CC=C(C2=CC3(CCNCC3)OC4=C2C=CC=C4)C(O)=C1

Molecular Formula

C24H28N2O3

Molecular Weight

392.49

References & Citations

[1]Le Bourdonnec B, et al. Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N, N-diethyl-3-hydroxy-4- (spiro [chromene-2, 4′-piperidine]-4-yl) benzamide (ADL5747) [J]. Journal of medicinal chemistry, 2009, 52 (18) : 5685-5702.