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LY88074

LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner[1].

Product Specifications

CAS Number

[177744-96-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/ly88074.html

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(O)C=C4

Molecular Formula

C21H14O4S

Molecular Weight

362.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Bivi N, et al. Structural features underlying raloxifene's biophysical interaction with bone matrix. Bioorg Med Chem. 2016 Feb 15;24 (4) :759-67.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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