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Ubiquitin Isopeptidase Inhibitor I, G5

Ubiquitin Isopeptidase Inhibitor I, G5 (NSC 144303) is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively.

Product Specifications

CAS Number

[108477-18-5]

Product Name Alternative

NSC144303

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Ubiquitin_Isopeptidase_Inhibitor_I,_G5.html

Purity

98.0

Solubility

Acetone : 2.86 mg/mL (ultrasonic) |DMSO : 25 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic) |THF : 3.44 mg/mL (ultrasonic)

Smiles

O=C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)/C(CS1(=O)=O)=C/C3=CC=C([N+]([O-])=O)C=C3

Molecular Formula

C19H14N2O7S

Molecular Weight

414.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Aleo E, et al. Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res. 2006 Sep 15;66 (18) :9235-44.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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