PDE10A-IN-2 (hydrochloride)
PDE10A-IN-2 hydrochloride is a potent, highly selective and orally active phosphodiesterase 10A (PDE10A) inhibitor with an IC50 of 2.8 nM. PDE10A-IN-2 hydrochloride shows selectivity of >3500-fold against other PDE subtypes. PDE10A-IN-2 hydrochloride can be used for pulmonary arterial hypertension (PAH) research[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pde10a-in-2-hydrochloride.html
Purity
98.43
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1CCN(CCCOC2=CC(N3C(/C=C/C4=C5N=CC=CC5=CC=C4)=NC6=CC(C)=CC=C36)=CC=C2)CC1.[H]Cl.[H]Cl.[H]Cl
Molecular Formula
C33H38Cl3N5O
Molecular Weight
627.05
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10
Available Sizes
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