POPSO,99% with 2H2O

POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].

Product Specifications

CAS Number

[68189-43-5]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/popso.html

Purity

99.0

Solubility

1M NaOH : 100 mg/mL (ultrasonic; adjust pH to 11 with 1M NaOH)

Smiles

O=S(O)(CC(CN1CCN(CC(CS(=O)(O)=O)O)CC1)O)=O

Molecular Formula

C10H22N2O8S2

Molecular Weight

362.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143 (1) :29-37.|[2]Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19 (10) :2542-2550.|[3]Kebede N, et al. Electrogenerated chemiluminescence of tris (2,2' bipyridine) ruthenium (II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140 (21) :7142-5.