(Rac) -Etavopivat
(Rac) -Etavopivat ((Rac) -FT-4202) is an isomer of Etavopivat (HY-139573) . Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies[1].
Product Specifications
CAS Number
[2622070-93-1]
Product Name Alternative
(Rac) -FT-4202
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rac-etavopivat.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(CO)C1=CC=CC=C1)N2CC3=C(CN(S(=O)(C4=CN=C5OCCOC5=C4)=O)C3)C2
Molecular Formula
C22H23N3O6S
Molecular Weight
457.50
References & Citations
[1]Patricia Schroeder, et al. Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease. J Pharmacol Exp Ther. 2022 Mar;380 (3) :210-219.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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