Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Baloxavir-d5

Baloxavir-d5 is deuterium labeled Baloxavir. Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity[1][2].

Product Specifications

Product Name Alternative

Baloxavir acid-d5; S-033447-d5

UNSPSC

12352005

Target

Influenza Virus; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O=C1N2[C@](COCC2)([H])N([C@]3([2H])C4=C([2H])C([2H])=C([2H])C([2H])=C4SCC5=C(F)C(F)=CC=C35)N6C1=C(O)C(C=C6)=O

Molecular Formula

C24H14D5F2N3O4S

Molecular Weight

488.52

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Dec;160:109-117.|[3]Omoto S, et al. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018 Jun 25;8 (1) :9633.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

50X TAE Buffer
EC-872 1 L

50X TAE Buffer

Sign In for Pricing
View Details
FGF2 Recombinant Rabbit Monoclonal Antibody [JM28-10]
ET1703-18 100 µL

FGF2 Recombinant Rabbit Monoclonal Antibody [JM28-10]

Sign In for Pricing
View Details
Cytokeratin 8 (KRT8) (KRT8/2174R), 0.2mg/mL
BNUB2174-500 1x 500 µL

Cytokeratin 8 (KRT8) (KRT8/2174R), 0.2mg/mL

Sign In for Pricing
View Details
4-Butoxyphenol
TRC-B690590-5G 5 g

4-Butoxyphenol

Sign In for Pricing
View Details
DdCTP [2',3'-Dideoxycytidine-5'-triphosphate] *10 mM in ddH2O*
17207-AAT 1 µmole

DdCTP [2',3'-Dideoxycytidine-5'-triphosphate] *10 mM in ddH2O*

Sign In for Pricing
View Details
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1485), CF640R conjugate, 0.1mg/mL
BNC401485-500 1x 500 µL

DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1485), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details