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Bis-PEG10-NHS ester

Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

2221949-02-4

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-peg10-nhs-ester.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Molecular Formula

C32H52N2O18

Molecular Weight

752.76

Precautions

H302, H315, H319, H335

References & Citations

[1]John L. Magnani, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

Available Sizes

Frequently Asked Questions

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