S-2720
S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection[1].
Product Specifications
CAS Number
146739-86-8
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-2720.html
Smiles
O=C(N1C2=CC(Cl)=CC=C2NC(C1(C)C)=S)OC(C)=C
Molecular Formula
C14H15ClN2O2S
Molecular Weight
310.80
References & Citations
[1]Kleim JP, et al. Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Antimicrob Agents Chemother. 1993 Aug;37 (8) :1659-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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