Human BTK Protein, His Tag (active enzyme)
Human BTK Protein, His Tag (BTK-H55H3) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ser 659 (Accession # Q06187-1) .
Product Specifications
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.2 kDa. The protein migrates as 55 kDa, 65 kDa and 85-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q06187-1
Expression Region
Met 1 - Ser 659
Host
Insect Cells
Target
BTK
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Liquid
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Glycerol
Molecular Weight
78.2 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/BTK-H55H3.pdf
Species
Human
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