Human BTK Protein, His Tag (active enzyme)

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.2 kDa. The protein migrates as 55 kDa,65 kDa and 85-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q06187-1

Expression Region

Met 1 - Ser 659

Host

Insect Cells

Target

BTK

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Additives

Glycerol

Molecular Weight

78.2 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

InsectCells

Species

Human

Protein ID

Q06187-1

Preservative

Glycerol

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