Almotriptan

Almotriptan is a selective agonist of 5-HT 1B/1D Receptor. Almotriptan can used in study of migraine attacks[1].

Product Specifications

CAS Number

[154323-57-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Almotriptan.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(CC1=CC2=C(NC=C2CCN(C)C)C=C1)(N3CCCC3)=O

Molecular Formula

C17H25N3O2S

Molecular Weight

335.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Bou J, et al. Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine. Eur J Pharmacol, 2000. 410 (1) : p. 33-41.|[2]Gras J, et al. Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics. Arzneimittelforschung, 2001. 51 (9) : p. 726-32.