FHT-2344
Product Specifications
UNSPSC Description
FHT-2344 is a SMARCA4/SMARCA2 ATPase inhibitor with IC50 values of 0.026 μM and 0.013 μM, respectively. FHT-2344 has anticancer activity[1].
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fht-2344.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](COC)C(NC2=NC(C3=CC(C4=NN(C=C4)C)=CC=C3)=CS2)=O
Molecular Weight
528.60
References & Citations
[1]Centore R C, et al. Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers[J]. bioRxiv, 2023: 2023.09. 11.557162.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149458/FHT-2344-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149458/FHT-2344-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2468058-90-2
Available Sizes
Curated Selection
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