FHT-2344
FHT-2344, a chemical probe, is a SMARCA4/SMARCA2 ATPase inhibitor with IC50 values of 0.026 μM and 0.013 μM, respectively. FHT-2344 has anticancer activity[1].
Product Specifications
CAS Number
[2468058-90-2]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fht-2344.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(C=C1)S(C)(=O)=O)N[C@@H](COC)C(NC2=NC(C3=CC(C4=NN(C=C4)C)=CC=C3)=CS2)=O
Molecular Formula
C23H24N6O5S2
Molecular Weight
528.60
References & Citations
[1]Centore R C, et al. Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers[J]. bioRxiv, 2023: 2023.09. 11.557162.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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