endo-BCN-PEG3-NHS ester
Product Specifications
UNSPSC Description
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/endo-bcn-peg3-nhs-ester.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1C2CCC#CCCC12)NCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O
Molecular Weight
494.53
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140068/endo-BCN-PEG3-NHS-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140068/
Clinical Information
No Development Reported
CAS Number
2101206-94-2
Available Sizes
Curated Selection
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