BS3 Crosslinker (disodium)
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[127634-19-9]
UNSPSC
12352203
Hazard Statement
H302, H315, H319
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bs3-crosslinker-disodium.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCCCC(ON2C(C(S(=O)(O[Na])=O)CC2=O)=O)=O
Molecular Formula
C16H18N2Na2O14S2
Molecular Weight
572.43
Precautions
H302, H315, H319
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
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