PROTAC MDM2 Degrader-3
Product Specifications
UNSPSC Description
PROTAC MDM2 Degrader-3 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-3 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
Target Antigen
E1/E2/E3 Enzyme; MDM-2/p53; PROTACs
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-mdm2-degrader-3.html
Purity
96.06
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C(N1CC(N(CC(OCCOCCOCCOCCOC(CN2C(CN(C(N3[C@H](C4=CC=C(Cl)C=C4)[C@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@H](C8=CC=C(Cl)C=C8)[C@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
Molecular Weight
1437.25
References & Citations
[1]Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128842/PROTAC-MDM2-Degrader-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128842/PROTAC-MDM2-Degrader-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2249750-23-8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Norovirus GII Matched Antibody Pair Set [ABP-S-05349]](https://cdn.genprice.uk/genprice/genprice3.png)
