Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

V-9302 (hydrochloride)

V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells[1].

Product Specifications

CAS Number

2416138-42-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ASCT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/v-9302-hydrochloride.html

Purity

99.10

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O)[C@@H](N)CCN(CC1=CC=CC=C1OCC2=CC=CC(C)=C2)CC3=CC=CC=C3OCC4=CC=CC(C)=C4.[H]Cl

Molecular Formula

C34H39ClN2O4

Molecular Weight

575.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Schulte ML, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacyin preclinical models. Nat Med. 2018 Feb;24 (2) :194-202.|[2]Jin H, et al. A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer. Elife. 2020;9:e56749. Published 2020 Oct 5.|[3]Edwards DN, et al. Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer. J Clin Invest. 2021;131 (4) :e140100.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ASCT2

Citation 01

Biochem Pharmacol. 2025 Feb 7:116796.|Biochem Pharmacol. 2025 Jun 7:117047.|J Nanobiotechnology. 2022 May 6;20 (1) :216.|Research Square Print. 2023 Jan 31.|Adv Sci (Weinh) . 2024 Dec 16:e2411479.|Adv Sci (Weinh) . 2025 Aug 10:e07057.|Autophagy. 2025 Jul 23:1-16.|Biomaterials. 2025 Sep 17:326:123726.|bioRxiv. 2024 July 05.|bioRxiv. 2025 Jul 31:2025.07.28.667320.|Cell Death Dis. 2024 Feb 5;15 (2) :111.|Cell Metab. 2022 Dec 6;34 (12) :1999-2017.e10.|Cell. 2024 Oct 31;187 (22) :6251-6271.e20.|FASEB J. 2025 Jul 15;39 (13) :e70774.|Front Pharmacol. 2021 May 14;12:671328.|J Biol Chem. 2022 Apr;298 (4) :101753.|J Control Release. 2023 May:357:460-471.|J Gastroenterol. 2025 Oct 8.|J Virol. 2025 Nov 25;99 (11) :e0098525.|Magn Reson Imaging. 2022 Nov:93:189-194.|Nano Today. 2025 Apr.|Nat Immunol. 2024 Oct;25 (10) :1845-1857.|Npj Imaging. 2025 Aug 1;3 (1) :34.|Pharmaceutics. 2024 Jun 29;16 (7) :877.|Proc Natl Acad Sci U S A. 2024 Mar 26;121 (13) :e2319429121.|University of Maryland. 2024.|University of Regensburg. 2024 Jul 18.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MKP-5 (G-10) AC
sc-374276 AC 500 µg/mL - 25% ag

MKP-5 (G-10) AC

Sign In for Pricing
View Details
BPHL antibody
70R-16020 50 μL

BPHL antibody

Sign In for Pricing
View Details
Fancg (NM_001163233) Mouse Tagged ORF Clone Lentiviral Particle
MR219937L3V 200 µL

Fancg (NM_001163233) Mouse Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
SNRPA1 protein (His tag)
80R-2103 10 ug

SNRPA1 protein (His tag)

Sign In for Pricing
View Details
Olr1179 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV629057 1.0 µg DNA

Olr1179 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

Sign In for Pricing
View Details
DKC1 (Dyskeratosis Congenita 1, Dyskerin, DKC, CBF5, DKCX, NAP57, NOLA4, XAP101) (APC)
MBS6414177-01 0.1 mL

DKC1 (Dyskeratosis Congenita 1, Dyskerin, DKC, CBF5, DKCX, NAP57, NOLA4, XAP101) (APC)

Sign In for Pricing
View Details