FStAx-35R (TFA)
FStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research[1].
Product Specifications
UNSPSC
12352209
Target
Wnt; β-catenin
Type
Peptides
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fstax-35r-tfa.html
Purity
97.35
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@H](CCCNC(N)=N)NC(COCCOCCNC(NC1=CC2=C(C3(OC2=O)C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)C=C1)=S)=O)N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C(N8CCC[C@H]8C(N[C@@H](CCCNC(N)=N)C(N[C@](C)(C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H]9CC(O)=O)=O)=O)=O)CCC/C=C/CCC[C@@](C)(C(N[C@@H](CC%10=CN=CN%10)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC%11=CNC%12=C%11C=CC=C%12)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C136H198N42O27S.xC2HF3O2
Molecular Weight
2885.36 (free base)
References & Citations
[1]Cui HK, et al., Design of stapled α-helical peptides to specifically activate Wnt/β-catenin signaling. Cell Res. 2013 Apr;23 (4) :581-4.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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