Mouse IL-6 protein

Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants

Product Specifications

Background

Gene ID

16193

Accession Number

P08505

Applications

No tag

Purity

> 99 % as determined by SDS-PAGE

Activity

Measured in a cell proliferation assay using M-NFS60. The ED50 for this effect is typically 1.75 ng/mL.The specific activity of recombinant Mouse IL6 is approximately >5.71 x 105IU/mg.

Molecular Formula

21.9 kDa

Molecular Weight

21.9 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Mouse IL-6 consists of 187 amino acids and predicts a molecular mass of 21.9 kDa

Formulation

Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 7.4.

Applications Notes

Mouse

Other Product Names

Mouse IL-6 protein、IL-6

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions