Human IL-4 protein

Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13. IL-4, originally designated as B-cell growth factor-1 (BSFl), is described in the supernatant of activated EL-4 thymoma cells as a factor that can co-stimulate B-cells activated with submitogenic concentrations of anti-IgM.

Product Specifications

Background

Gene ID

3565

Accession Number

P05112

Applications

No tag

Purity

> 96 % as determined by SDS-PAGE

Activity

Measured in a cell proliferation assay using TF-1. The ED50 for this effect is typically 0.144 ng/mL. The specific activity of recombinant Human IL4 is approximately >6.94 x 106IU/mg

Molecular Formula

15.1 kDa

Molecular Weight

15.1 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: <1 EU per μg of the protein by the LAL metho

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Human IL-4 consists of 129 amino acids and predicts a molecular mass of 15.1 kDa.

Formulation

Lyophilized from sterile 20 mM Tris-HCl, 150 mM NaCl, pH 7.4.

Applications Notes

Human

Other Product Names

Human IL-4 protein、IL-4

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions