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(R) -MK-8353

Product Specifications

CAS Number

2748457-30-7

Target

ERK

Related Pathways

MAPK

Bioactivity

(R) -MK-8353 ((R) -SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective, orally active inhibitor of ERK1 and ERK2, with IC50 values of 23.0 nM and 8.8 nM, respectively.

Smiles

N(C(=O)[C@]1(SC)CN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=NN(C)C=N4)CC1)C=5C=C6C(=NNC6=CC5)C=7C=CC(OC(C)C)=NC7

Molecular Formula

C37H41N9O3S

Molecular Weight

691.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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