Mono (2-ethyl-5-hydroxyhexyl) terephthalate
Product Specifications
CAS Number
1684398-38-6
Target
Drug Metabolite
Related Pathways
Metabolism
Bioactivity
Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP) is a hydroxy metabolite of Di-2-ethylhexyl terephthalate (DEHTP) and acts as an agonist of the liver X receptor α (LXRα) with a binding energy of -7.41 kcal/mol. MEHHTP upregulates downstream targets of LXRα, including SREBP-1c and FASN, enhancing lipogenic enzyme activity and increasing triglyceride (TG) levels in hepatocytes. This compound shows potential for research in non-alcoholic fatty liver disease (NAFLD) .
Smiles
O=C(O)C1=CC=C(C=C1)C(=O)OCC(CC)CCC(O)C
Molecular Formula
C16H22O5
Molecular Weight
294.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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