(S) -Padsevonil
Product Specifications
CAS Number
1294001-37-8
Target
GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
(S) -Padsevonil is the S-enantiomer of Padsevonil. Padsevonil (UCB0942) is a potent antiepileptic agent that selectively targets both presynaptic and postsynaptic sites. It binds with high affinity to synaptic vesicle protein 2 (SV2) and acts as a positive allosteric modulator and partial agonist of GABAAR, showing greater efficacy on receptors containing α1 and α5 subunits. Padsevonil demonstrates antiepileptic effects in various rodent models.
Smiles
C(C=1N2C(=NC1C(F)(F)F)SC(COC)=N2)N3C[C@H](CC(Cl)(F)F)CC3=O
Molecular Formula
C14H14ClF5N4O2S
Molecular Weight
432.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TSW-00612-01 100 mg
β-D-Mannopyranoside, octyl,2,3,4,6-tetraacetate
Sign In for Pricing
View Details TSW-00612-02 250 mg
β-D-Mannopyranoside, octyl,2,3,4,6-tetraacetate
Sign In for Pricing
View Details