What is the catalog number for (Rac) -Vepdegestrant?

The catalog number for (Rac) -Vepdegestrant is TYD-02806.

What sizes are available for (Rac) -Vepdegestrant?

(Rac) -Vepdegestrant is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does (Rac) -Vepdegestrant come in?

(Rac) -Vepdegestrant is available in 2 different pack sizes.

Is (Rac) -Vepdegestrant in stock?

(Rac) -Vepdegestrant is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures (Rac) -Vepdegestrant?

(Rac) -Vepdegestrant is manufactured by Molfinity.

What is the estimated delivery time for (Rac) -Vepdegestrant?

Estimated delivery time for (Rac) -Vepdegestrant is approximately 10 business day(s), depending on your location.

(Rac) -Vepdegestrant

Product Specifications

CAS Number

2229711-08-2

Target

Estrogen Receptor/ERR, PROTACs

Related Pathways

Endocrinology/Hormones, PROTAC

Bioactivity

(Rac) -Vepdegestrant is an isomer of Vepdegestrant. Vepdegestrant ((Rac) -ARV-471) is an orally active estrogen receptor PROTAC degrader used against breast cancer. It is a heterobifunctional molecule that facilitates the interaction between estrogen receptor α and the intracellular E3 ligase complex. Vepdegestrant induces ubiquitination and subsequent degradation of the estrogen receptor via the proteasome, effectively degrading ER in ER-positive breast cancer cell lines with a DC50 value of approximately 2 nM.