(R, R) -LRRK2-IN-7
Product Specifications
CAS Number
2307277-92-3
Target
LRRK2
Related Pathways
Autophagy
Bioactivity
(R, R) -LRRK2-IN-7 is an isomer of LRRK2-IN-7, a potent and selective LRRK2 kinase inhibitor with CNS penetrance. It exhibits an IC50 of 0.9 nM and demonstrates over 1000-fold selectivity compared to other kinases, ion channels, and CYP enzymes.
Smiles
C(#N)[C@]1(C2(C1)CC2)C=3C=C4N(N=CC4=CC3)C=5C=C(N=CN5)N6C[C@H](C(C)(C)O)CC6
Molecular Formula
C24H26N6O
Molecular Weight
414.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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