3,4-Dibromo-Mal-PEG4-Acid
Product Specifications
CAS Number
2434639-17-3
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
3,4-Dibromo-Mal-PEG4-Acid is a site-specific ADC linker featuring a dibromomaleimide group and an acid group. The presence of two bromine atoms in the dibromomaleimide group allows for two substitution points. In the presence of EDC and HATU, the carboxylic acid can react with primary amines to form stable amide bonds. The hydrophilic PEG linker enhances the compound's solubility in aqueous media.
Smiles
O=C(O)CCOCCOCCOCCOCCN1C(=O)C(Br)=C(Br)C1=O
Molecular Formula
C15H21Br2NO8
Molecular Weight
503.137
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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