Heptadecan-9-amine

Heptadecan-9-amine (9-Aminoheptadecane) is a PEG linker featuring maleimide and TFP ester terminal groups. The maleimide group reacts with thiols at a pH between 6.5 and 7.5, while the TFP ester can interact with primary amine groups and is less susceptible to hydrolysis than NHS esters. The hydrophilic PEG chain enhances the compound's solubility in aqueous media, with longer PEG chains offering improved solubility compared to shorter ones.