DBCO-PEG4-Val-Ala-PAB-PNP
Product Specifications
CAS Number
2348405-93-4
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala dipeptide sequence can be cleaved by cathepsin B. The DBCO group is typically utilized in click chemistry reactions. The PEG spacer enhances the compound's solubility in water. PNP serves as an effective leaving group.
Smiles
C(CCC(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)C)=O)[C@H](C)C)=O)=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4
Molecular Formula
C52H60N6O14
Molecular Weight
993.065
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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