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DBCO-PEG4-Val-Cit-PAB-PNP

Product Specifications

CAS Number

2226472-28-0

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker where Val-Cit is specifically cleaved by Cathepsin B. The PNP group can be substituted by amine-containing payloads, and DBCO undergoes click chemistry reactions with azide molecules.

Smiles

C(CCC(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4

Molecular Formula

C55H66N8O15

Molecular Weight

1079.16

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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