PT-ttpy
Product Specifications
CAS Number
727721-37-1
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
Pt-ttpy is a metallo-organic compound and an effective G-quadruplex ligand that efficiently induces significant telomere-associated DNA damage in cancer cells by inhibiting telomerase and/or telomere function. It also causes various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFB), and double-stranded breaks (DSB) .
Molecular Formula
C22H17Cl2N3Pt
Molecular Weight
589.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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