DL-4-Hydroxy-2-ketoglutarate

DL-4-Hydroxy-2-ketoglutarate (DL-4KG) is a gamma-keto acid as well as a structural analogue of glutamic acid that functions as a biochemical substrate for enzymes such as 4-hydroxy-2-oxoglutarate aldolase (HOGA1) and glutamic-oxaloacetic transaminase (GOT), DL-4-Hydroxy-2-ketoglutarate also serves as a lysine analogue used in mechanistic studies of enzyme inhibition and metabolic pathways.