6-Aminopenicillanic acid

6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses[1][2][3][4].

Product Specifications

CAS Number

[551-16-6]

Product Name Alternative

6-APA

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Drug Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6-aminopenicillanic-acid.html

Purity

98.0

Solubility

0.1 M HCl : 12.5 mg/mL (ultrasonic; adjust pH to 2 with HCl) |0.1 M NaOH : 5 mg/mL (ultrasonic) |H2O : 0.33 mg/mL (ultrasonic)

Smiles

[C@H]12SC([C@@H](N1C(=O)[C@H]2N)C(=O)O)(C)C

Molecular Formula

C8H12N2O3S

Molecular Weight

216.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Lucie Vobecká, et al. Optimization of Aqueous Two-Phase Systems for the Production of 6-aminopenicillanic Acid in Integrated Microfluidic Reactors-Separators. N Biotechnol. 2018 Dec 25;47:73-79.