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8-Br-dGTP sodium

Product Specifications

Target

Nucleoside Antimetabolite/Analog

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

8-Br-dGTP (8-Bromo-dGTP) sodium (Compound 5) is a cis isomer of dGTP, characterized as an 8-bromoguanosine nucleotide. This compound is hydrolyzed by the enzyme hMTH1 protein. It inhibits dGTP-activated ADP reduction, exhibiting a Ki value of 56 μM. During DNA synthesis, 8-Br-dGTP sodium presents no significant genotoxicity or mutagenic potential.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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