3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite
Product Specifications
CAS Number
1644649-86-4
Target
DNA/RNA Synthesis, Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.
Smiles
C(N[C@@H]1[C@@H](COP(N(C(C)C)C(C)C)OCCC#N)O[C@H](C1)N2C=3C(N=C2)=C(N=CN(C)C)N=CN3)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6
Molecular Formula
C41H50N9O3P
Molecular Weight
747.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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