Lipopolysaccharides, from S. enterica serotype typhimurium

Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium, are endotoxins and TLR4 activators derived from the serotype of this bacterium, classified as S-type LPS. They display a characteristic three-part structure: O antigen, core oligosaccharide, and lipid A. These lipopolysaccharides influence bacterial fate within dendritic cells (DC), determining the uptake, degradation, and activation of immune functions in DC cells.