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2-Hydroxyalbrassitriol

2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC50 of 35.97 μM[1].

Product Specifications

CAS Number

[1176586-98-3]

UNSPSC

12352211

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2-hydroxyalbrassitriol.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](O)(C(C)=C[C@@H]([C@@]1([H])C(C)(C[C@@H](C2)O)C)O)CO

Molecular Formula

C15H26O4

Molecular Weight

270.36

References & Citations

[1]Xu K, et al. Cadinane- and drimane-type sesquiterpenoids produced by Paecilomyces sp. TE-540, an endophyte from Nicotiana tabacum L., are acetylcholinesterase inhibitors. Bioorg Chem. 2020 Nov;104:104252.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

AChE

Curated Selection

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