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PI3Kα-IN-23

PI3Kα-IN-23 (Compound 9) is an inhibitor of PI3Ka H1047R[1].

Product Specifications

UNSPSC

12352005

Target

Akt; PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3kα-in-23.html

Solubility

10 mM in DMSO

Smiles

CC1=CC2=C(N=C(C3CC4=C(C=CC=C4)C3)N(C)C2=O)C(C(C)NC5=CC=CC=C5C(O)=O)=C1

Molecular Formula

C28H27N3O3

Molecular Weight

453.53

References & Citations

[1]James F et al. Preparation of ((4-oxo-3,4-dihydroquinazolin-8-yl) methyl) amine derivatives as PI3K inhibitors for the treatment of cancer. World Intellectual Property Organization, WO2024064024 A1 2024-03-28

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kα

Frequently Asked Questions

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