PI3Kα-IN-23
PI3Kα-IN-23 (Compound 9) is an inhibitor of PI3Ka H1047R[1].
Product Specifications
UNSPSC
12352005
Target
Akt; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-23.html
Solubility
10 mM in DMSO
Smiles
CC1=CC2=C(N=C(C3CC4=C(C=CC=C4)C3)N(C)C2=O)C(C(C)NC5=CC=CC=C5C(O)=O)=C1
Molecular Formula
C28H27N3O3
Molecular Weight
453.53
References & Citations
[1]James F et al. Preparation of ((4-oxo-3,4-dihydroquinazolin-8-yl) methyl) amine derivatives as PI3K inhibitors for the treatment of cancer. World Intellectual Property Organization, WO2024064024 A1 2024-03-28
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα
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