γ-Hexalactone

γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage and acts a substrate of paraoxonase 1 (PON1) [1][2][3].

Product Specifications

CAS Number

[695-06-7]

Product Name Alternative

γ-Caprolactone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gamma-hexalactone.html

Purity

99.77

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OC(CC)CC1

Molecular Formula

C6H10O2

Molecular Weight

114.14

Precautions

H302, H315, H319, H335

References & Citations

[3]Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019 Jul;93 (7) :2035-2043.|[1]E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel) . 2018 Mar 2;18 (3) .|[2]Bianchi T, et al. Investigation of the aroma of commercial peach (Prunus persica L. Batsch) types by Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and sensory analysis. Food Res Int. 2017 Sep;99 (Pt 1) :133-146.