TP53 neoepitope
Product Specifications
CAS Number
151808-74-1
Target
MHC
Related Pathways
Immunology/Inflammation
Bioactivity
TP53 neoepitope is a high-affinity antigen peptide that targets HLA-A and is capable of activating CD8+ T cell-mediated cytotoxicity against TP53-mutant tumor cells. It holds promise for research involving solid tumors harboring TP53 hotspot mutations (such as R175H, R273H) .
Smiles
[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CCSC)=O)[C@@H](C)O)=O)CCC(O)=O)=O)C(C)C)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(O)=O)CS)=O
Molecular Formula
C45H74N16O13S2
Molecular Weight
1111.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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